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Cannabis Endo

CANNABIS

Cannabis has been used for its beneficial qualities for thousands of years for medicinal, spiritual, recreational and industrial purposes. Historically, it was used medicinally to treat a variety of ailments including pain, nausea, and inflammation. Today, it is still used globally for all these benefits including its psychoactive effects, primarily to induce relaxation, reduce stress, and improve mood. It is also used medicinally to treat conditions such as chronic pain, anxiety, and many other conditions. Cannabis is most commonly consumed by smoking, or ingested in various forms, including edibles and oils.

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Background on Medicinal Cannabis

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Cannabis has a long and colorful history.

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It is a plant of the Cannabaceae family and its medicinal properties have been known for millennia.

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Cannabis was first thought to have originated from Central Asia and was used by many ancient societies.

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In fact, indications for therapeutic use of cannabis were mentioned in the texts of the Indian Hindus, Assyrians, Greeks and Romans. Cannabis was described to have helped alleviate and treat many health ailments, including pain, depression, inflammation, appetite loss and asthma related problems et cetera.

How does Medicinal Cannabis work?

The Cannabis plant contains two of the most prominent cannabinoids;

Cannabidiol (CBD) and Delta-9-Tetrahydrocannabinol (THC).

Through the Endocannabinoid System in our body, CBD and THC interact to have various effects.

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Doctor and patient
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The Endocannabinoid System

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The endocannabinoid system (ECS) is a complex cell-signalling system found throughout our body.

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It consists of three key components, including:

 

Endocannabinoids

  • Molecules created by our body

  • Help keep internal functions running smoothly

 

Receptors

  • Receptors found throughout our body

  • Two key receptors

    1. CB1 - mainly found in central nervous system

    2. CB2 - mainly found in peripheral nervous system

  • Endocannabinoids bind to either receptor & effects depend on where the receptor is located

 

Enzymes

Responsible for breaking down endocannabinoids once they have served their function

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The endocannabinoid system plays a critical role in balancing many processes in our body, including immune response, appetite, sleep, et cetera.

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